When Antonio Brown celebrated his first touchdown with New England by vaulting into a first-row luxury box, he didn't linger. The Patriots had a job to finish.

Determined to play to the final gun after allowing a miracle comeback at Miami last year, the Patriots beat the Dolphins 43-0 Sunday.

Bill Belichick had Tom Brady still throwing at the end.

"We're playing 60 minutes," the New England coach said.

The Patriots did that. They scored twice on interception returns in a two-minute fourth-quarter span, and they registered their first shutout since Week 3 of 2016.

Brown helped get them going. The Patriots (2-0) were 18½-point favorites but led Miami (0-2) only 7-0 late in the first half before Brady hit his newest target for a 20-yard score. Brown and Brady connected four times for 56 yards in all, all in the first half.

"It was a good start," Brady said. "I was just trying to find an open guy. He was snapping off some routes and did a great job."

Brown didn't talk to reporters after the game. The NFL let the four-time All-Pro play despite a lawsuit filed Tuesday by his former trainer accusing him of sexually assaulting her on three occasions. Brown has denied the allegations.

Kansas City 28, Oakland 10: Patrick Mahomes bounced back from the first scoreless opening quarter of his career in the regular season by throwing four touchdown passes in a near-perfect second quarter, and the Chiefs (2-0) beat the host Raiders (1-1). Mahomes finished with 443 passing yards.

Houston 13, Jacksonville 12: Justin Reid stopped Leonard Fournette on a two-point conversion attempt with 36 seconds left and the host Texans (1-1) held off the Jaguars (0-2).

Indianapolis 19, Tennessee 17: Jacoby Brissett threw a 4-yard touchdown pass to T.Y. Hilton with 4:38 left in Nashville and the Colts (1-1) continued their dominance of the Titans (1-1).

NFC

Prescott does it all

Dallas 31, Washington 21: Dak Prescott completed 26 of 30 passes for 269 yards and three touchdowns and also ran for 69 yards for the Cowboys (2-0) vs. the host Redskins (0-2), who got a rushing TD from Adrian Peterson and two TD passes from Case Keenum. With Prescott leading the way, Dallas had consecutive TD drives of 97, 83 and 75 yards.

Philadelphia at Atlanta, late: The Eagles were hit hard by injuries in the first half, with receivers Alshon Jeffery (calf) and DeSean Jackson (groin) and tight end Dallas Goedert (calf) going to the sidelines. Quarterback Carson Wentz returned after being evaluated for a concussion.

Interconference

49ers go 2-0 on road

San Francisco 41, Cincinnati 17: Jimmy Garoppolo threw three TD passes and the 49ers (2-0) completed a week in the Buckeye State by beating the host Bengals (0-2). Rather than return to California after a Week 1 victory at Tampa Bay, the 49ers went to Youngstown, Ohio, to prepare for this game; it resulted in back-to-back road victories to open a season for the first time in 30 years.

Baltimore 23, Arizona 17: Lamar Jackson kept the Cardinals (0-1-1) guessing all day, supplementing an effective passing attack with more than an occasional jaunt out of the pocket for the host Ravens (2-0).

Buffalo 28, N.Y. Giants 14: Josh Allen ran for a touchdown, threw for another, and the Bills (2-0) claimed state bragging rights by beating the Giants (0-2) in East Rutherford, N.J.