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Last update: October 22, 2007 - 10:32 PM

Ev3 Inc., the Plymouth-based maker of medical devices that acquired FoxHollow Technologies Inc. this month, said it expects to incur a "significant net loss" in the fourth quarter as a result of restructuring charges and other business integration-related expenses. It also cut its fiscal 2008 sales and profit forecasts. Fourth-quarter sales will be $108 million or more, Ev3 said. Ev3 said it revised its fiscal 2008 forecasts, in part, because it has not yet received U.S. marketing clearance for FoxHollow's RockHawk, a calcium-cutting device to remove plaque from arteries, and is unable to estimate the approval date. Fiscal 2008 profit, excluding acquisition-related expenses, will be at least 55 cents a share on sales of $570 million or more, Ev3 said. That's down from 60 to 70 cents a share on $585 million to $615 million in sales, which the company previously expected.

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